Theta power is increased in 5-HT1AR knock-out mice during exposure to the elevated plus maze. Mean ± SEM of theta power (A, C, E) and peak frequency (B, D, F) during exposure to the elevated plus maze (A, B), a familiar environment (C, D), and during REM sleep in the home cage (E, F). For the elevated plus maze and familiar environment, power is calculated separately for epochs divided by the speed of the animal. Filled diamonds, 5-HT1AR knockouts; open squares, wild types. n = 10-14 animals per group.