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NMDA increasingly dissipates ΔΨm at progressively lower O2 concentrations. Before NMDA, cultures were equilibrated in one of four O2 concentrations, during which time TMRM changes were measured every 20 s. No changes in baseline TMRM fluorescence intensity ratios occurred at any O2 concentration used. Progressively greater mean peak ΔΨm dissipation was observed as O2 concentration decreased. *p < 0.05.
