Figure 5.

The combination of zymosan pretreatment and ChABC promotes significant regeneration across the DREZ. A, At 14 d after injury in the combination treatment group, significant regeneration (arrow) is demonstrated across the DREZ (red). B, The ChABC injection site is identified by 2-B-6 staining (green) representing digested CSPGs. Regenerating axons appear to be drawn to the region of greatest CSPG digestion (compare A, B). C, Three-dimensional reconstruction of regenerating axons demonstrating the extent of rostral/caudal regeneration. Scale bars, 30 μm.