Skip to main content
. 2005 Jan 12;25(2):488–495. doi: 10.1523/JNEUROSCI.4127-04.2005

Figure 2.

Figure 2.

a-c, Colocalization of GRs (a) and NR1 (b), as shown in the emerged image (c), was observed in the ipsilateral spinal cord dorsal horn of a representative CCI rat. The sample was taken at day 7 after CCI. DL, Dorsal lateral part of the dorsal horn. Scale bar, 60 μm. d, e, The GR antagonist RU38486 (2 μg, i.t.) given twice daily on postoperative days 1-6 attenuated the expression of NR1 (Western blot) within the ipsilateral spinal cord dorsal horn of CCI rats, when examined on postoperative day 7. *p < 0.05, compared with sham rats. S/V, Sham plus vehicle; C/V, CCI plus vehicle; C/RU, CCI plus RU38486. RU38486 alone did not change the baseline NR1 expression (data not shown).