Figure 1.
Representative images of Reelin-induced enhancement of Ca2+ influx in cortical neurons. Representative images of fura-2 AM 340/380 ratios of Ca2+ transients induced by 40 μm glutamate in cortical neurons are shown. A pseudocolored calibration scale for 340/380 ratios is shown on the right. All recordings were performed in ACSF supplemented with TTX, nimodipine, and CNQX. Wild-type neurons were recorded without (first row) and with (second row) Reelin treatment. Fura-2 AM 340/380 ratio images are shown 30 s before (first column) and 30 s after (second column), 1.5 min after (third column), and 3 min after (fourth column) application of 40 μm glutamate.