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. 2005 Sep 7;25(36):8165–8172. doi: 10.1523/JNEUROSCI.1816-05.2005

Figure 4.

Figure 4.

Effect of TRP and citalopram (CIT) coadministered on immobility time and accumulation of brain 5-HTP and DOPA in DBA/2J (a,b) and BALB/c (c,d) mice. Mice received vehicle (VEH) or 300 mg/kg intraperitoneal tryptophan 30 min before saline or 5 mg/kg citalopram (CIT) and were tested 30 min after citalopram (a, c; n = 10 per group). The effect of 30–300 mg/kg tryptophan on 5-HTP and DOPA accumulation in DBA/2J (b) and BALB/c (d) mice was assessed in separate groups of six mice. Data are means ± SEM. *p < 0.05 versus respective vehicle; °p < 0.05 versus citalopram (Tukey-Kramer's test).