Figure 4.

Effects of hippocampal inactivation on extinction training and testing did not differ across contexts. A, Freezing behavior averaged across the first 3, middle 3, and final 3 post-CS minutes of the extinction training session. All rats were fear conditioned in context A. Extinction training occurred the next day, in either the same context as conditioning (A→A; circles) or a new context (context B; A→B; squares) after infusions of either muscimol (open symbols) or saline (filled symbols). B, Renewal of fear to the CS was similar among all INCON/SAL, CON/MUS, and INCON/MUS groups, relative to the CON/SAL group (CON groups, open bars; INCON groups, filled bars). Muscimol and saline refer to infusions given before extinction training. All data are presented as means ± SEM.