Table 1.
|
α3-/- |
Control |
---|---|---|
Small clear synaptic vesicles (nm, diameter) | 30 ± 1.5 | 33 ± 1.2 |
Large dense core vesicles (nm, diameter) | 71 ± 3.3 | 71 ± 5.6 |
Docked vesicles (# per synapse) | 0.9 ± 0.3 | 1.1 ± 0.2 |
Multivesicular bodies (# per synapse) | 0.7 ± 0.2 | 0.5 ± 0.3 |
Synaptic cleft width (nm, diameter) | 25 ± 1.2 | 24 ± 0.7 |
Active zone length (nm, diameter) | 261 ± 30 | 263 ± 22 |
PSD length (nm, diameter) |
265 ± 19 |
273 ± 29 |
Data represent means ± SEMs; n = 29 α3-/- synapses and 36 control synapses from 9 α3-/- and 6 control animals, respectively. Docked vesicles per synapse are defined as those that are located less than one vesicle diameter from the presynaptic plasma membrane. PSD, Postsynaptic density.