Figure 6.

Voltage-independent inhibition of R6(R). A, Currents evoked by 1 μm kainate (open bar) at -70 and +40 mV were strongly blocked by 15 μm DHA (solid bar). Superimposed lines show the best fits of the sum of two exponentials plus a constant to block onset or one exponential plus a constant to recovery from block. B, Steady-state block by 15 μm DHA at -70 mV (open bar; n = 18 cells) and +40 mV (shaded bar; n = 14 cells). C, Time constants (left) and relative amplitudes (right) for exponential fits to onset of block and recovery from block. Error bars represent SEM.