Table 1.

List of HN derivatives

HN derivatives	Sequence	Effect (Aβ1-43)
HN	MAPRGFSCLLLLTSEIDLPVKRRA	10 μm
S14G-HN (HNG)	MAPRGFSCLLLLTGEIDLPVKRRA	10 nm
C8A-HN (HNA)	MAPRGFSALLLLTSEIDLPVKRRA	NE
d-Ser14 HN	MAPRGFSCLLLLT(dS)EIDLPVKRRA	10 nm
AGA-HNG	MAPAGASCLLLLTGEIDLPVKRRA	100-300 pm
AGA-(d-Ser14)HN	MAPAGASCLLLLT(dS)EIDLPVKRRA	100-300 pm
AGA-(d-Ser14)HN17	PAGASCLLLLT(dS)EIDLP	100 pm
AGA-(C8R)HNG17	PAGASRLLLLTGEIDLP	10 pm
EF-HN	EFLIVIKSMAPRGFSCLLLLTSEIDLPVKRRA	100 nm
EF-HNA	EFLIVIKSMAPRGFSALLLLTSEIDLPVKRRA	NE
EF-HNG	EFLIVIKSMAPRGFSCLLLLTGEIDLPVKRRA	1 nm
EF-AGA-HNG	EFLIVIKSMAPAGASCLLLLTGEIDLPVKRRA	10 pm
Colivelin	SALLRSIPA-PAGASRLLLLTGEIDLP	100 fm

The abbreviated names, sequences, and the potencies of the antagonizing effect of Aβ1-43-mediated neurotoxicity are indicated for each peptide. Effect indicates minimal concentration of each peptide that exerted full neuroprotection. NE, No protective effect.