Skip to main content
. 2005 Nov 9;25(45):10520–10536. doi: 10.1523/JNEUROSCI.2547-05.2005

Figure 5.

Figure 5.

Specific targeting of interneurons expressing a high level of the muscarinic acetylcholine M2 receptor by intensely mGluR8-immunoreactive terminals. A-C, Fluorescence micrographs showing interneurons immunolabeled for the M2 receptor (red) and receiving boutons immunopositive for mGluR8a or mGluR8b (green) on soma and dendrites in the CA1 stratum oriens/alveus [mGluR8a (A) and mGluR8b (C)] and in the CA3 stratum pyramidale (mGluR8a; B). D1-D3, Consecutive electron micrographs showing an mGluR8a-immunoreactive (peroxidase product) bouton establishing a type II synapse (large arrow) with a M2-immunoreactive (gold/silver particles; small arrows) dendritic shaft in the CA1 stratum oriens/alveus. E1-E3, Consecutive electron micrographs showing an M2-immunoreactive (gold/silver particles; small arrows) dendritic shaft in the CA1 stratum oriens/alveus receiving a type II synapse (large arrow) from an axon terminal immunoreactive for both mGluR8a (peroxidase labeled) and M2 (gold/silver particles) on the plasma membrane (small arrows). F1-F4, Consecutive electron micrographs showing a mGluR8a-immunoreactive (peroxidase) bouton establishing a type I perforated synapse (arrowheads) with an M2-immunoreactive (gold/silver particles on the plasma membrane; small arrows) dendritic shaft in the CA1 stratum oriens/alveus. Scale bars: A, B, 30 μm; C, 10 μm; D1-D3, E1-E3, 0.5 μm; F1-F4, 0.2 μm. At, Axon terminal; d, dendritic shaft.