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. 2005 Nov 16;25(46):10598–10606. doi: 10.1523/JNEUROSCI.2990-05.2005

Table 2.

PIB binding to homogenates from 15-month-old PS1/APP and PS1 mice and human AD and control brain in the presence of 1 nm [3H]PIB




PIB bound (pmol/g wet weight)

Fold difference
PS1/APP (n = 4) 166 ± 61 3.5
PS1 (n = 4) 47.5 ± 51
Human AD (n = 4) 415 ± 51 16.3
Human control (n = 3)
25.4 ± 46