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. 2005 Nov 23;25(47):10922–10929. doi: 10.1523/JNEUROSCI.3766-05.2005

Figure 1.

Figure 1.

PMA application increased the frequency of miniature EPSCs (mEPSCs) in 15 DIV hippocampal cultures but not in 5 DIV cultures. Recordings were made before and 2 min after PMA application. A, B, Sample traces showing the mEPSCs before and after PMA application at 5 DIV. C, D, Frequency and amplitude of mEPSCs did not change after PMA treatment in 5 DIV hippocampal cultures (n = 7). E, F, Sample traces of whole-cell patch-clamp recordings showing mEPSCs obtained from neurons in 15 DIV hippocampal cultures. G, Two minute application of PMA increased the mEPSC frequency (n = 7 for each group). *p < 0.001. H, Amplitudes of mEPSCs did not change after 2 min of PMA treatment. Error bars indicate SE.