Constitutively active Akt promotes dendritic branching similar to PI3K. A, Representative micrographs of hippocampal neurons transfected with control vector, wild-type Akt (WT), constitutively active Akt (myr-Akt), or kinase-dead Akt (Akt-K179D). Neuronal morphology was visualized by cotransfected GFP. Age and duration of transfection are indicated. B, C, Sholl analysis of neurons transfected with control vector or Akt or PI3K constructs at various DIV as indicated.