Table 4.
NAA concentrations measured by 1H-MRSI and RP-HPLC from the midbrains of mice 2 d after MPTP treatment
|
|
Midbrain NAA levelsA |
||
|---|---|---|---|
| Treatment |
MRSI (mm) |
HPLC (μmol/g tissue) |
|
| PBS | 9.1 ± 0.4 | 16.5 ± 1.5 | |
| MPTP | 7.1 ± 0.2* | 11.0 ± 1.4 | |
| MPTP/Cop-1 | 9.3 ± 1.0 | 17.5 ± 2.3 | |
| MPTP/OVA |
7.6 ± 0.7*
|
13.7 ± 1.4 |
|
Mean ± SEM for five to nine mice per group.
p ≤ 0.05 compared with PBS-treated mice.