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. 2005 Feb 16;25(7):1750–1760. doi: 10.1523/JNEUROSCI.4217-04.2005

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Copyright © 2005 Society for Neuroscience 0270-6474/05/251750-11.00/0

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Figure 9. — Function of protein synthesis is required for induction of LTP-IE. A, Representative recordings of EPSCs (top traces) and APs (bottom traces) during control and 30 and 100 min after CS in the presence of emetine (5 μm). B, Pooled data showing the CS-induced changes in EPSPs (top) and AP threshold (bottom) in the presence of emetine (open diamond; n = 5 cells) or anisomycin (5 μm; open square; n = 5 cells) compared with data from time control cells (open circle). Inset, The mean AP amplitude in the presence of emetine (gray bar) and anisomycin (filled bar) compared with control cells (open bar) and the mean AHP amplitude before (open bar) and after CS in the presence of emetine (gray bar) or anisomycin (filled bar). ^*p < 0.05; paired t test.