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. 2005 Feb 2;25(5):1249–1259. doi: 10.1523/JNEUROSCI.1786-04.2005

Figure 3.

Figure 3.

Increased innervation of limb muscles in gephyrin-deficient mice. Motor axon branches (green) and acetylcholine receptor clusters (red) in the gluteus maximus muscle in wild-type (A, E18.5; C, E16; +/+) and gephyrin-deficient (B, E18.5; D, E16; -/-) mice are shown. E and F show the numbers (mean ± SEM) of gluteus maximus NMJs and branch bifurcations over the same muscle region for wild-type (white bars) and gephyrin-deficient (black bars) E18.5 and E16 mice. There were significantly more neuromuscular synapses and branch bifurcations in the gluteus maximus muscles from gephyrin-deficient mice compared with wild-type controls. *p < 0.05; **p < 0.01; n = 5; Student's t test. Scale bars: A, B, 100 μm; C, D, 50 μm.