Table 1.
Motoneuron numbers are decreased in respiratory nuclei and increased in limb-innervating nuclei in gephyrin-deficient mice (-/-) compared with wildtype mice (+/+)
|
|
+/+ |
-/- |
%Change |
|---|---|---|---|
| (V) Trigeminal | |||
| E15.5 | 2283 ± 176 (4) | 1710 ± 162 (4)* | -15 |
| E18.5 | 883 ± 29 (4) | 659 ± 97(3)** | -25 |
| (VII) Facial | |||
| E15.5 | 6904 ± 630 (3) | 7217 ± 640 (3) | +3 |
| E18.5 | 3067 ± 292 (5) | 2234 ± 138 (4)* | -27 |
| (XII) Hypoglossal | |||
| E15.5 | 4045 ± 523 (4) | 3181 ± 353 (4)* | -21 |
| E18.5 | 1279 ± 131 (3) | 867 ± 120 (4)* | -32 |
| Phrenic | |||
| E15.5 | 1125 ± 111 (3) | 707 ± 95(3)** | -37 |
| E18.5 | 653 ± 25 (3) | 458 ± 53(4)** | -30 |
| Brachial | |||
| E13.5 | 5235 ± 496 (3) | 5100 ± 199 (3) | -3 |
| E15.5 | 2584 ± 312 (4) | 3294 ± 353 (4)* | +27 |
| E18.5 | 1957 ± 267 (6) | 2393 ± 328 (6)* | +22 |
| Lumbar | |||
| E16 | 2489 ± 251 (3) | 3084 ± 228 (3)* | +24 |
| E18.5 |
2038 ± 107 (3) |
2793 ± 358(5)**
|
+37 |
Values represent the mean ± SD number of motoneurons. Values in parentheses show the number of animals examined. *p<0.05; **p<0.01; t test.