Table 2.
Spontaneous neural activity is increased for hypoglossal (XII) nerve and decreased for lumbar 5 nerve in gephyrin-deficient mice (-/-) compared with wild-type mice (+/+)
|
|
XII nerve |
L5 nerve |
||||
|---|---|---|---|---|---|---|
|
|
+/+ (n = 6) |
-/- (n = 4) |
+/+ (n = 9) |
-/- (n = 7) |
||
| Burst frequency (Hz) | 0.0285 ± 0.0171 | 0.0648 ± 0.0287* | 0.0872 ± 0.0588 | 0.0209 ± 0.0065* | ||
| Peak burst amplitude (V) | 0.700 ± 0.41 | 1.30 ± 1.05 | 0.81 ± 0.34 | 1.35 ± 0.76 | ||
| Burst half-width (ms) | 88.74 ± 46.27 | 119.29 ± 13.52 | 95.54 ± 19.87 | 103.03 ± 22.01 | ||
| Burst 10-90% rise time (ms) | 99.05 ± 47.44 | 138.25 ± 29.20 | 203.55 ± 141.78 | 100.65 ± 57.98 | ||
| Burst 10-90% decay time (ms) | 166.17 ± 54.81 | 262.02 ± 79.10 | 302.88 ± 134.9 | 273.82 ± 191.01 | ||
| Burst area (V/ms) | 138.35 ± 94.04 | 356.19 ± 131.55 | 298.40 ± 162.39 | 280.01 ± 205.71 | ||
| Mean nerve activity (charge/min) |
0.0732 ± 0.0668 |
0.3433 ± 0.1309*
|
0.4087 ± 0.3120 |
0.1001 ± 0.0795*
|
||
*
p < 0.05; Student's t test.