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. 2005 Feb 9;25(6):1442–1447. doi: 10.1523/JNEUROSCI.4041-04.2005

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Copyright © 2005 Society for Neuroscience 0270-6474/05/251442-06.00/0

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Figure 3. — Noxa-deficient mice showed rescue from motor neuron death. A, Number of neurons in hypoglossal nuclei (uninjured) from littermate control (Noxa^+/+) and Noxa-deficient (Noxa^-/-) mice. Values represent means ± SD (n = 6). B, Thionine staining of hypoglossal motor neurons 35 d after hypoglossal nerve injury in Noxa^+/+ and Noxa^-/- mice. Scale bar, 50 μm. C, Survival of motor neurons from Noxa^+/+ and Noxa^-/- mice 35 d after axotomy. Results represent the percentage ratio of surviving motor neurons on the operated side compared with those on the contralateral side. Noxa^+/+ (n = 10) and Noxa^-/- (n = 9) were significantly different (^*p < 0.01; t test).