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. 2005 Dec 14;25(50):11553–11563. doi: 10.1523/JNEUROSCI.3362-05.2005

Figure 2.

Figure 2.

Bath application of GABA enhances the tonic GABAA current. A, Trace recorded from a dLGN TC neuron under control conditions showing a small outward shift (ΔIGBZ = 35.4 pA) in baseline current after focal GBZ application (white bar). B, In a different TC neuron recorded in the presence of bath-applied GABA (1 μm), GBZ application causes a larger shift in baseline current (ΔIGBZ = 81.5 pA). C, In a VB TC neuron recorded in the presence of 5 μm extracellular GABA, GBZ application causes a massive shift in baseline current (ΔIGBZ = 159.0 pA). D, Graph showing the comparison of ΔIGBZ amplitude under control conditions and in the presence of 1 μm GABA in dLGN TC neurons (white columns), and under control conditions, in the presence of 1μm GABA, and in the presence of 5μm GABA in VBTC neurons (black columns). Calibration in A also applies to B and C. ***p < 0.001 compared with control, Student's unpaired t test.