Figure 2.

A 5 min reexposure to the training context triggers memory reconsolidation but not extinction. A, Experimental procedure for anisomycin administration. The white box represents a 30 s tone, the arrow indicates the foot shock, and the syringe indicates the intraperitoneal injection of anisomycin. B, Systemic anisomycin (Ani) administration immediately after a 5 min reexposure significantly reduced contextual freezing assessed 24 h after the reexposure (n_saline = 12; n_{ani(150 mg/kg)} = 9; n_{ani (250 mg/kg)} = 8). Data are means ± SEM; ^*p < 0.05. C, Reexposure to the context did not induce contextual memory extinction in the saline group.