Skip to main content
. 2005 Feb 23;25(8):1935–1942. doi: 10.1523/JNEUROSCI.4707-04.2005

Figure 3.

Figure 3.

SGK1 mRNA expression in the hippocampus is upregulated after contextual fear conditioning and reexposure to the context. A, qPCR showed that SGK1 mRNA expression was upregulated in the hippocampus 1 h after contextual fear conditioning and 1 h after context-shock memory reactivation compared with the naive and T+25 group. B, SGK1 mRNA expression in the hippocampus did not significantly differ in the Box, LI, and T+1 groups. Thus, the upregulation after conditioning was not specific for the learned association. (The naive and T+1 groups are the same as in A.) C, SGK1 mRNA expression in the hippocampus significantly differed in the Box R+1 versus R+1 and in the T+25 versus Box R+1 groups. Thus, upregulation of SGK-1 expression after reexposure appeared to be induced in part by the context alone and in part by fear or by context-shock memory reactivation. Data are means ± SEM; *p < 0.05; **p < 0.01.