Skip to main content
. Author manuscript; available in PMC: 2019 Sep 4.
Published in final edited form as: Anesth Analg. 2019 May;128(5):1013–1021. doi: 10.1213/ANE.0000000000004058

Figure 5.

Figure 5.

Morphine and opioid antagonist effects on natural killer (NK) cytolytic function. The cytolytic function of NK cells was determined by measuring the percentage of apoptotic K562 cells in experimental wells (white bars) stained for annexin V compared to the percentage in positive control wells containing NK cells and K562 target cells without any drug treatment (=100% apoptosis, black bar). The gray bars indicate NK cell function after incubation with naloxone or opioid receptor-specific antagonists. Data are from 5 independent experiments conducted with NK cells from 5 separate donors in triplicate wells for each data point. n = 5; mean and upper limit of 95% CI are represented. Adjusted P values are reported. nor-BNI, nor-binaltorphimine dihydrochloride.