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. Author manuscript; available in PMC: 2019 Sep 4.
Published in final edited form as: Tuberculosis (Edinb). 2015 Dec 8;96:158–164. doi: 10.1016/j.tube.2015.10.006

Figure 2: Enrichment for lymphocytes responsive to Mtb antigens in BAL of healthy subjects with LTBI:

Figure 2:

Enrichment was calculated from the data displayed in Figure 1 using BAL cell differentials of each subject and the conservative assumption that lymphocytes accounted for 85% of PBMC samples in each case. Figures display the fold-differences in frequencies of antigen-responsive IFNγ-producing lymphocytes in these samples for each subject, again displayed as individual data (diamonds and circles), median values (dark lines) and range of 25th to 75th percentiles (shaded boxes). As described in the text, compared to results for control subjects, BAL of LTBI subjects displayed significant enrichment for IFNγ-producing cells in response to PPD, antigen 85B, and CFP-10, but not to ESAT-6.