Table 1. Patients’ characteristics at PB sampling.
| IgM MGUS (N = 21) N (%) Median (range) |
Untreated WM (N = 19) N (%) Median (range) |
Treated WM (N = 33) N (%) Median (range) |
P- value | |
|---|---|---|---|---|
| Median age (range) | 71(50–89) | 70 (61–89) | 70 (51–87) | 0.35 |
| Sex (M:F) | 15:6 | 17:2 | 25:8 | |
| PS (ECOG) 0–2 | 20 (95.2) | 18 (94.7) | 33 (100) | 0.19 |
| Adenopathy | 0 (0) | 2 (10.5) | 6 (18.1) | 0.69 |
| Symptomatic disease | 0 (0) | 5 (26.3) | 4 (12.5) | 0.089 |
| Hemoglobin (g/dL) | 13.2 (10.1–16.0) | 12.3 (7.6–16.3) | 12.4 (7.5–15.6) | 0.31 |
| Serum IgM (mg/dL) | 742.5 (110–2426) | 1425 (140–11940) | 1271 (42–9790) | 0.14 |
| Serum LDH (mg/dL) | 183.5 (103–224) | 136 (52–240) | 179 (92–267) | 0.12 |
| Serum β2MG (mg/dL) | 2.0 (1.2–5.3) | 2.8 (1.8–7.3) | 2.45 (1.4–5.6) | 0.059 |
| Platelet count (x104/mm3) | 23.9 (4.3–51.1) | 19.9 (4.2–44.3) | 19.5 (2.1–48.1) | 0.36 |
| Peripheral lymphocyte count (/mm3) | 1710 (594–3808) | 1620 (836–15075) | 1170 (59–5893) | 0.015 |