TABLE I.
Characteristics of the study patients at baseline
| Characteristic | Value |
|---|---|
| Patients | |
|
| |
| Mean age (years) | 57.4±10.5 |
|
| |
| Mean body mass index (kg/m2) | 28.5±4.9 |
|
| |
| Mean heart rate (bpm) | 79±13 |
|
| |
| Mean blood pressure (mmHg) | |
| Systolic | 135±22 |
| Diastolic | 78±9 |
|
| |
| Sex [n (%) women] | 18 (100) |
|
| |
| Cancer stage [n (%)] | |
| IA | 2 (11) |
| IB | 2 (11) |
| IIA | 8 (44) |
| IIB | 2 (11) |
| IIIA | 2 (11) |
| IV | 2 (11) |
|
| |
| Cardiac risk factors [n (%)] | |
| Coronary artery disease | 1 (6) |
| Diabetes | 2 (11) |
| Dyslipidemia | 2 (11) |
| Hypertension | 3 (17) |
| History of smoking | 4 (22) |
| Valvular heart disease | 0 |
| Previous heart failure | 0 |
|
| |
| NYHA class on presentation [n (%)] | |
| I | 16 (89) |
| II | 2 (11) |
| Tumour | |
|
| |
| Receptor status [n (%)] | |
| ER-positive | 11 (61) |
| PgR-positive | 8 (44) |
| ER- or PgR-negative | 7 (39) |
|
| |
| Left-sided disease [n (%)] | 12 (67) |
|
| |
| Previous radiation therapy [n (%)] | 17 (94) |
|
| |
| Previous anthracycline treatment [n (%)] | 17 (94) |
|
| |
| Recurrent disease [n (%)] | 2 (11) |
NYHA = New York Heart Association; ER = estrogen receptor; PgR = progesterone receptor.