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. 2019 Aug 1;26(4):e458–e465. doi: 10.3747/co.26.4583

TABLE II.

Characteristics of 9 patients with highly suspicious integrated 18F-fluorodeoxyglucose positron-emission tomography (PET) and computed tomography imaging

Pt Age (years) Sex Paraneoplastic neurologic syndrome Antibody Area of abnormality on imaging Malignancy in OCR Informative (yes or no)
1 60 Female Cerebellar ataxia Anti-Hu Mediastinal node, left hilar node Lung malignancy, polycythemia vera Yes
2 76 Female Encephalitis, sensory neuropathy Anti-Hu Mediastinal node Not present No (no identified malignancy)
3 62 Male Sensory neuropathy Not tested Supraclavicular node, gastrohepatic node Brain NOS, lung malignancy Yes
4 76 Female Cerebellar ataxia Not tested Nasopharynx, thyroid lobe, LUL nodule, LLL nodule Not present No (no identified malignancy)
5 44 Male Limbic encephalitis Negative Global increased uptake in axial skeleton Myelodysplastic syndrome Yes
6 53 Female Limbic encephalitis, sensory neuropathy Anti-Hu Bilateral hilar nodes, mediastinal nodes, low level uptake in atelectasis, LLL subpleural node Cancer of unknown primary Yes
7 80 Male Limbic encephalitis Not reported Paratracheal node Cancer of unknown primary No (biopsy preceded PET imaging)
8 62 Female Peripheral neuropathy, encephalitis Not tested LUL consolidation, peripancreatic node, external iliac node, pubic bone, sacrum Lung cancer Yes
9 52 Female Ataxia, tremor Negative Diffuse activity in liver, spleen; focal activity in hepatic hilum, para-aortic node; increased marrow activity Previous diagnosis of kidney, thyroid cancer No (biopsy preceded PET imaging)

Pt = patient; OCR = Ontario Cancer Registry; NOS = not otherwise specified; LUL = left upper lobe, LLL = left lower lobe