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. Author manuscript; available in PMC: 2020 Apr 9.
Published in final edited form as: J Am Coll Cardiol. 2019 Apr 9;73(13):1673–1687. doi: 10.1016/j.jacc.2018.12.086

Figure 4: Group A – Early intervention protocol: changes in physical activity in TBX18 antegrade biological pacemaker-treated animals compared to controls.

Figure 4:

(A-B) Representative 24-hour activity plots at endpoint from an implanted accelerometer. (C) Mean 24-hour activity at endpoint (365±27au GFP, 421.5±27.7au TBX18 p=0.1). (D-E) Burst activity was considered spontaneous high levels of activity (>2000 a.u.). TBX18 animals demonstrated higher frequency (6 ±1 episodes GFP, 8.8±1 episodes TBX18, p=NS) and duration of burst activity (124±21.2s GFP, 183.8±13.4s TBX18, p=0.06). (F) Describes the period between high levels of burst activity. The latency period between bursts of activity was superior in TBX18 pigs (69.53min GFP, 45±2min TBX18, p=0.005).