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. Author manuscript; available in PMC: 2020 Sep 4.
Published in final edited form as: ChemMedChem. 2019 Jul 24;14(17):1597–1603. doi: 10.1002/cmdc.201900344

Scheme 2.

Scheme 2.

Synthesis of mixed aryl acyloxy phosphonate esters. Reagents and conditions: (a) ArOH, Et3N, 82% for 11, 35% for 13; (b) POMCl, NaI, reflux, 31% for 11, 28% for 13 ; (c) SeO2, tBuOOH, rt, 12% for 12, 9% for 14.