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. Author manuscript; available in PMC: 2020 Oct 15.
Published in final edited form as: Dev Biol. 2019 Jun 23;454(2):156–169. doi: 10.1016/j.ydbio.2019.06.012

Fig. 10: Gene expression of key developmental pathway components are equivalent between Adamts18−/− and wildtype embryonic kidneys and lungs.

Fig. 10:

A-H: Expression of Spry2 and Shh (A, B, E, F) and Fgf10 and Bmp4 (C, D, G, H) in E12.5 kidneys (A-D) and lungs (E-H) from wildtype and Adamts18−/− embryos utilizing RNAscope probes. For each tissue, staining was collected from three different embryos with three images quantified from each. The number of transcripts were manually counted for three cell populations: tip, stalk, and non-ureteric bud (kidneys) or non-epithelial (lungs). I: The average transcripts per cell was quantified for each probe; in all cases there was no (continued on next page) significant difference between wildtype and Adamts18−/− tissue samples. Error bars are SD and significance was determined by a two-tailed t-test. N-UB = non-ureteric bud; N-Ep = non-epithelial. Line = 500μm.