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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Cancer Immunol Res. 2019 Jul 24;7(9):1497–1510. doi: 10.1158/2326-6066.CIR-18-0489

Figure 3: VISTA overexpression in human monocyte THP-1 cells inhibits the activation of MAPKs and NF-κB following TLR2 stimulation.

Figure 3:

Human monocyte THP-1 cells overexpressing VISTA (THP-1VISTA) and control cells (THP-1Ctrl) were stimulated with Pam3Cys4 (10 μg/mL) for the indicated amount of time. (A-B) Total cell lysates were generated and examined by Western blotting. Phosphorylated (p-) Jnk1/2, Erk1/2, p38, IKKα/β, and NF-κBp65, and total IκB were quantified by Image J software and shown in panel C. Shown are representative results from at least three independent repeats.