Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Validation of the changes in expression of stemness genes caused by metformin in HNSCC cells. A. Validation of the stemness genes (SOX2/ALDH1A1/BMI1/CD44/CD133) expression in the indicated HNSCC cells treated with or without metformin in vitro, measured by qPCR. (*, P<0.05; **, P<0.01; ***, P<0.001; mean ± SD.) B. The cell lysates were used to evaluate the expression of the protein product of stemness genes in response to metformin and the impact of methyl-pyruvate treatment as in A.
