Date	Event	Description
5 September 2014	New search has been performed	Searches conducted. We identified no new trials for inclusion.
5 September 2014	New citation required but conclusions have not changed	Our conclusions remain unchanged.
16 April 2013	Feedback has been incorporated	Feedback comment and reply added to the review.
20 November 2012	Amended	Headings for Figures have been correctly labelled.
7 August 2012	New citation required but conclusions have not changed	A new team of authors has taken over this previously withdrawn review.
7 August 2012	New search has been performed	Due to this review update's focus on registered trademark Oscillococcinum®, the conclusions on prevention are based on different studies from those in previous versions of this review (i.e. Selkova 2005a and Selkova 2005b instead of Attena 1995 and Nollevaux 1990). Nevertheless, the results of our meta‐analyses are similar to the previous publication of this review, Vickers 2006, and the fundamental conclusion is unchanged: current evidence does not support a preventive effect of Oscillococcinum® in influenza and influenza‐like illness. Our focus solely on reported trial data, without reference to data or other information that was missing from the original trial reports, has had an impact on our reporting of the main outcome measure for the treatment studies. Mean duration of influenza illness cannot be extracted from the two relevant papers, Ferley 1989 and Papp 1998, so patient‐reported symptom relief at 48 hours is the most closely comparable primary outcome measure we can report. Again, the adjusted focus does not alter the fundamental conclusion: Oscillococcinum® may have a beneficial treatment effect above that of placebo but the clinical importance of any such effect is unclear. Rigorous assessment of the eligible studies has designated the evidence overall as 'low quality'.
19 April 2008	Amended	Converted to new review format.
27 February 2006	New search has been performed	Searches conducted. Electronic literature searches were repeated in February 2006; one additional trial was found and excluded.
24 June 2003	New search has been performed	Searches conducted.
10 March 2003	Feedback has been incorporated	Response to feedback added to review.
4 March 2003	Feedback has been incorporated	Feedback added to review.
27 February 2001	New search has been performed	Searches conducted.
20 February 1999	New search has been performed	Searches conducted.