Casanova 1984.

Methods	Randomised, placebo‐controlled trial of Oscillococcinum® in the treatment of influenza‐like illness
Participants	100 participants with influenza‐like illness onset less than 48 hours previously No details of method of recruitment or exclusion criteria Average age of Oscillococcinum/placebo groups: 42/41 years Males:females in Oscillococcinum/placebo groups: 19:31/26:24
Interventions	Oscillococcinum®, 4 doses in over 2 days at 6‐hour intervals
Outcomes	Participant global assessment of success; presence of chills, aches, rhinitis, night cough, day cough, fever at day 8
Notes	Reported in what appears to be a general medical magazine: very few experimental details given Research setting: France (unspecified location)
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No statement about randomisation
Allocation concealment (selection bias)	Unclear risk	No description of allocation procedure
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	No description of blinding procedure
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	No description of blinding procedure
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Insufficient information provided
Selective reporting (reporting bias)	Unclear risk	Insufficient information provided
Other bias	Unclear risk	Insufficient information provided