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. 2019 Aug 30;5(8):e02095. doi: 10.1016/j.heliyon.2019.e02095

Fig. 1.

Fig. 1

The morphological change of HeLa cells undergoing division in highly hypotonic environment. The red arrows indicate the retracting of the cytokinetic furrow: (a) The HeLa cell was cultured in isotonic DMEM till its telophase and then the medium was replaced by 5% PBS at time 0 min. Morphological reversal occurred. At 62 min the cell was cultured again in isotonic DMEM and the cell finally became binuclear. (b) The HeLa cell was cultured in isotonic DMEM till its telophase and then the medium was replaced by 5% PBS at time 0 min. Morphological reversal occurred. At 46 min the cell was cultured again in isotonic DMEM and the cell started a secondary division and finally finished the division.