Fig. 7.

Proof of principle of proton-dynamic cell death in glioblastoma cell lines using cercosporin as the photosensitiser (PS). Differential cell death of M059K (a) and T98G (b) human glioblastoma cell lines, for varying radiation doses (2–5 Gy) with/without PS (cercosporin 4–10 μM, 4 h incubation), vs. their respective controls. The grey bars depict cell groups without PS while the magenta bars depict cell groups with PS. These results showcase the best experiments so far (3 parallels). Errors are represented as standard errors of the mean. c Box plot illustrating the increase in proton-dynamic differential cell death (cells without PS vs with PS) from all experiments conducted on M059K and T98G cells. The magenta line shows the mean of all experiments while the black line represents the median. The error bars represent s.e.m. Source data for a, b are provided as Source Data files