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. 2019 Jul 23;110(9):2982–2991. doi: 10.1111/cas.14114

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© 2019 The Authors Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Representative image of phosphorylated STAT3 (pSTAT3)‐positive lymphoma cells in Pautrier's microabscess. The sample was obtained from a skin lesion in a 51‐y‐old man with smoldering type adult T‐cell leukemia/lymphoma (ATLL). The aggregated lymphoma cells in a Pautrier's microabscess (arrow) showed stronger pSTAT3 expression compared with those in the dermis (arrowhead) (original magnification, ×200). This finding indicates that extracellular stimuli such as cytokines might influence pSTAT3 expression in ATLL cells located in Pautrier's microabscess