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Schematic representation of the 2 different oncogenic pathways involved in the lymphoma type of adult T‐cell leukemia/lymphoma (ATLL). Nuclear phosphorylated STAT3 (pSTAT3) expression is the distinguishing characteristic between the progressed lymphoma type (expresses pSTAT3, similar to acute and smoldering types) and de novo lymphoma type (does not express pSTAT3), suggesting the existence of at least 2 oncogenic molecular mechanisms. HTLV‐1, human T‐cell leukemia virus type I
