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. 2019 Jul 23;110(9):2875–2883. doi: 10.1111/cas.14117

Table 5.

Total dose and relative dose intensity

  SOX P CS P
Male Female Male Female
(n = 221) (n = 73) (n = 221) (n = 81)
S‐1
RDI (%) Median 83.7 75.0 .029a 83.3 83.3 .411a
  [Range] [17.0‐114.5] [13.0‐100]   [2.4‐112.9] [11.9‐101.7]  
  Mean, SD 81.4, 20.6 75.4, 21.6 .032b 79.6, 22.7 84.0, 18.0 .081b
Oxaliplatin/cisplatin
RDI (%) Median 98.3 75.0 .077a 87.5 87.5 .958a
  [Range] [0‐100] [28.0‐100]   [0‐134.6] [0‐102.9]  
  Mean, SD 83.5, 20.0 79.1, 20.0 .100b 80.3, 30.2 82.1, 27.2 .636b

SOX for 3 cycles, CS for 2 cycles.

Abbreviations: CS; S‐1 plus cisplatin, RDI, relative dose intensity; SD, standard deviation; SOX, S‐1 plus oxaliplatin.

a

Wilcoxon rank sum test.

b

t‐test.