Figure 2.

Circular RNA circCRIM1 suppresses the invasion and migration of lung adenocarcinoma cell lines in vitro. A, Expression of circCRIM1 in LUAC cell lines as determined by quantitative real‐time PCR. B, Quantitative real‐time PCR analysis of circCRIM1 RNA expression after treatment with circCRIM1 siRNAs and overexpression plasmids. C‐E, circCRIM1 reduced cell migration and invasion as determined by Transwell and Matrigel (C), wound healing (D), and real‐time cell analysis (E) assays. NC, negative control