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. 2019 Jun 27;47(8):3690–3698. doi: 10.1177/0300060519849295

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Low levels of lncRNA HAND2-AS1 and IGF-1 were significantly correlated with poor survival.

Plasma levels of IGF-1 and lncRNA HAND2-AS1 as measured by ELISA and RT-qPCR were analyzed by the unpaired t test. Patients who survived the follow-up period (n=22) had significantly higher levels of HAND2-AS1 (a) and IGF-1 (b) than those who died (n=26) (*, P<0.04). Survival analysis showed that low levels of lncRNA HAND2-AS1 (c) and IGF-1 (d) were significantly correlated with poor survival in patients with end-stage DCM.