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. 2019 Jul 16;47(8):3860–3873. doi: 10.1177/0300060519860026

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Effects of electroacupuncture (EA) on serum cytokine levels in rats with postoperative cognitive dysfunction (POCD): (a) Serum S-100β and (b) serum NSE levels were significantly increased at days 1, 3, and 7 following POCD induction; and (c) serum BDNF and (d) serum GDNF levels were significantly decreased at days 1, 3, and 7 following POCD induction. Electroacupuncture significantly attenuated the changes in all four cytokines versus the POCD model group. Data presented as mean ± SD; n = 8 per group; *P < 0.05 versus day 0 (pre-surgery) in the same group; #P < 0.05 versus model group at the same time points (one-way analysis of variance). S-100β, S100 calcium binding protein B; NSE, neuron-specific enolase; BDNF, brain-derived neurotrophic factor; GDNF, glial cell-derived neurotrophic factor.