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. 2019 Aug 7;110(9):2760–2772. doi: 10.1111/cas.14136

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© 2019 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Downregulation of TP53TG1 inhibits pancreatic ductal adenocarcinoma (PDAC) cell migration and invasion. A, Wound‐healing assays were carried out to determine the migratory ability of si‐TP53TG1‐transfected PANC‐1 and MIA PaCa‐2 cells. **P < .01, ***P < .001. B, Effect of TP53TG1 downregulation on the invasive abilities of PANC‐1 and MIA PaCa‐2 cells was measured using Transwell assays. ***P < .001. C, Colony formation assays were carried out to determine the anchorage‐independent growth abilities of PANC‐1 and MIA PaCa‐2 cells after TP53TG1 knockdown. **P < .001. NC, negative control