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. 2019 Jul 10;40(2):99–110. doi: 10.1007/s10974-019-09536-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — The Lethocerus thick filament and troponin bridges. a Cryo-EM image of a relaxed IFM thick filament. Myosin heads form crowns spaced at 14.5 nm along the filament. The IHM is nearly perpendicular to the filament axis, with the blocked head projecting furthest from the filament. The bare zone of the filament is at the top. Scale bar 10.0 nm. b Averaged images of IFM during isometric contraction. Crossbridges are fitted with atomic models of a myosin head and Tn bridges are not. Tn is orange and Tm is yellow. Tn bridges contact the thin filament at or near Tn. a is from Hu et al. (2017); b is from Wu et al. (2010)