Table 4.
Systemic Exposure Dosage (SED) |
Margin of Safety (MoS) |
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Cd | Pb | Cr | Cu | Co | Ni | Mn | Zn | Fe | Cd | Pb | Cr | Cu | Co | Ni | Mn | Zn | Fe | |
Household detergents | ||||||||||||||||||
HD1 | 3.44 × 10−4 | 2.58 × 10−3 | 0.00 | 2.01 × 10−3 | 3.73 × 10−3 | 4.01 × 10−3 | 0.00 | 1.40 × 10−2 | 6.48 × 10−2 | 2.91 × 105 | 1.55 × 105 | 0.00 | 1.99 × 106 | 8.05 × 103 | 4.98 × 105 | 0.00 | 2.14 × 106 | 1.08 × 106 |
HD2 | 4.59 × 10−4 | 2.87 × 10−3 | 0.00 | 1.72 × 10−3 | 4.01 × 10−3 | 3.73 × 10−3 | 1.72 × 10−3 | 1.83 × 10−2 | 7.11 × 10−2 | 2.18 × 105 | 1.40 × 105 | 0.00 | 2.33 × 106 | 7.48 × 103 | 5.37 × 105 | 8.14 × 106 | 1.64 × 106 | 9.85 × 105 |
HD3 | 3.44 × 10−4 | 2.01 × 10−3 | 0.00 | 2.29 × 10−3 | 4.30 × 10−3 | 4.30 × 10−3 | 0.00 | 2.95 × 10−2 | 7.85 × 10−2 | 2.91 × 105 | 1.99 × 105 | 0.00 | 1.74 × 106 | 6.98 × 103 | 4.65 × 105 | 0.00 | 1.02 × 106 | 8.91 × 105 |
HD4 | 3.10 × 10−3 | 2.69 × 10−2 | 0.00 | 3.15 × 10−3 | 4.59 × 10−3 | 6.02 × 10−3 | 4.01 × 10−3 | 4.62 × 10−2 | 1.85 × 10−1 | 3.23 × 104 | 1.48 × 104 | 0.00 | 1.27 × 106 | 6.54 × 103 | 3.32 × 105 | 3.49 × 106 | 6.50 × 105 | 3.79 × 105 |
HD5 | 5.73 × 10−4 | 3.15 × 10−3 | 0.00 | 2.29 × 10−3 | 5.45 × 10−3 | 7.17 × 10−3 | 1.72 × 10−3 | 3.07 × 10−2 | 9.80 × 10−2 | 1.74 × 105 | 1.27 × 105 | 0.00 | 1.74 × 106 | 5.51 × 103 | 2.79 × 105 | 8.14 × 106 | 9.78 × 105 | 7.14 × 105 |
HD6 | 8.60 × 10−4 | 5.73 × 10−3 | 0.00 | 1.15 × 10−3 | 3.73 × 10−3 | 5.16 × 10−3 | 0.00 | 1.81 × 10−2 | 7.40 × 10−2 | 1.16 × 105 | 6.98 × 104 | 0.00 | 3.49 × 106 | 8.05 × 103 | 3.88 × 105 | 0.00 | 1.66 × 106 | 9.46 × 105 |
HD7 | 4.01 × 10−4 | 5.16 × 10−3 | 3.44 × 10−3 | 2.29 × 10−3 | 3.15 × 10−3 | 4.59 × 10−3 | 1.72 × 10−3 | 1.32 × 10−2 | 1.61 × 10−1 | 2.49 × 105 | 7.75 × 104 | 8.72 × 104 | 1.74 × 106 | 9.51 × 103 | 4.36 × 105 | 8.14 × 106 | 2.28 × 106 | 4.36 × 105 |
HD8 | 5.16 × 10−4 | 2.87 × 10−3 | 1.85 × 10−2 | 4.30 × 10−3 | 4.30 × 10−3 | 6.88 × 10−3 | 8.31 × 10−3 | 2.09 × 10−2 | 1.15 × 10−1 | 1.94 × 105 | 1.40 × 105 | 1.63 × 104 | 9.30 × 105 | 6.98 × 103 | 2.91 × 105 | 1.68 × 106 | 1.43 × 106 | 6.07 × 105 |
HD9 | 5.73 × 10−4 | 9.46 × 10−3 | 1.80 × 10−2 | 1.43 × 10−3 | 4.01 × 10−3 | 6.88 × 10−3 | 5.73 × 10−3 | 2.95 × 10−2 | 9.69 × 10−2 | 1.74 × 105 | 4.23 × 104 | 1.67 × 104 | 2.79 × 106 | 7.48 × 103 | 2.91 × 105 | 2.44 × 106 | 1.02 × 106 | 7.22 × 105 |
HD10 | 1.03 × 10−3 | 1.38 × 10−2 | 5.73 × 10−4 | 2.87 × 10−3 | 5.45 × 10−3 | 8.60 × 10−3 | 6.88 × 10−3 | 2.58 × 10−2 | 1.08 × 10−1 | 9.69 × 104 | 2.91 × 104 | 5.23 × 105 | 1.40 × 106 | 5.51 × 103 | 2.33 × 105 | 2.03 × 106 | 1.16 × 106 | 6.46 × 105 |
Household liquid soaps | ||||||||||||||||||
HLS11 | 1.43 × 10−3 | 8.89 × 10−3 | 1.66 × 10−3 | 0.00 | 5.73 × 10−4 | 3.44 × 10−3 | 0.00 | 1.98 × 10−2 | 3.58 × 10−2 | 6.98 × 104 | 4.50 × 104 | 1.80 × 105 | 0.00 | 5.23 × 104 | 5.81 × 105 | 0.00 | 1.52 × 106 | 1.96 × 106 |
HLS12 | 9.75 × 10−4 | 2.29 × 10−3 | 2.01 × 10−3 | 0.00 | 5.73 × 10−4 | 3.73 × 10−3 | 2.87 × 10−4 | 3.21 × 10−2 | 5.33 × 10−2 | 1.03 × 105 | 1.74 × 105 | 1.50 × 105 | 0.00 | 5.23 × 104 | 5.37 × 105 | 4.88 × 107 | 9.34 × 105 | 1.31 × 106 |
HLS13 | 2.29 × 10−4 | 2.58 × 10−3 | 7.45 × 10−4 | 2.87 × 10−4 | 2.87 × 10−3 | 0.00 | 2.87 × 10−3 | 1.81 × 10−2 | 4.57 × 10−2 | 4.36 × 105 | 1.55 × 105 | 4.03 × 105 | 1.40 × 107 | 1.05 × 104 | 0.00 | 4.88 × 106 | 1.66 × 106 | 1.53 × 106 |
Household bar soaps | ||||||||||||||||||
HBS14 | 7.45 × 10−4 | 1.43 × 10−3 | 0.00 | 1.15 × 10−3 | 1.72 × 10−3 | 3.44 × 10−3 | 8.60 × 10−4 | 2.78 × 10−2 | 1.19 × 10−1 | 1.34 × 105 | 2.79 × 105 | 0.00 | 3.49 × 106 | 1.74 × 104 | 5.81 × 105 | 1.63 × 107 | 1.08 × 106 | 5.90 × 105 |
HBS15 | 5.73 × 10−4 | 4.01 × 10−3 | 2.51 × 10−2 | 2.01 × 10−3 | 4.01 × 10−3 | 6.59 × 10−3 | 3.44 × 10−3 | 2.32 × 10−2 | 2.49 × 10−1 | 1.74 × 105 | 9.97 × 104 | 1.20 × 104 | 1.99 × 106 | 7.48 × 103 | 3.03 × 105 | 4.07 × 106 | 1.29 × 106 | 2.81 × 105 |
HBS16 | 3.44 × 10−4 | 3.15 × 10−3 | 0.00 | 8.60 × 10−4 | 1.72 × 10−3 | 3.44 × 10−3 | 3.15 × 10−3 | 2.21 × 10−2 | 9.98 × 10−2 | 2.91 × 105 | 1.27 × 105 | 0.00 | 4.65 × 106 | 1.74 × 104 | 5.81 × 105 | 4.44 × 106 | 1.36 × 106 | 7.02 × 105 |
HBS17 | 9.17 × 10−4 | 1.15 × 10−3 | 1.90 × 10−2 | 1.43 × 10−3 | 1.15 × 10−3 | 4.01 × 10−3 | 0.00 | 1.78 × 10−2 | 9.29 × 10−2 | 1.09 × 105 | 3.49 × 105 | 1.58 × 104 | 2.79 × 106 | 2.62 × 104 | 4.98 × 105 | 0.00 | 1.69 × 106 | 7.54 × 105 |
HBS18 | 2.87 × 10−4 | 2.87 × 10−4 | 0.00 | 1.15 × 10−3 | 1.43 × 10−3 | 4.01 × 10−3 | 6.88 × 10−3 | 2.44 × 10−2 | 1.18 × 10−1 | 3.49 × 105 | 1.40 × 106 | 0.00 | 3.49 × 106 | 2.09 × 104 | 4.98 × 105 | 2.03 × 106 | 1.23 × 106 | 5.93 × 105 |
HBS19 | 5.16 × 10−4 | 1.43 × 10−3 | 0.00 | 2.01 × 10−3 | 1.72 × 10−3 | 3.44 × 10−3 | 8.60 × 10−3 | 3.87 × 10−1 | 1.24 × 10−1 | 1.94 × 105 | 2.79 × 105 | 0.00 | 1.99 × 106 | 1.74 × 104 | 5.81 × 105 | 1.63 × 106 | 7.75 × 104 | 5.63 × 105 |
HBS20 | 1.26 × 10−3 | 1.43 × 10−3 | 0.00 | 0.00 | 3.15 × 10−3 | 4.30 × 10−3 | 0.00 | 1.81 × 10−2 | 1.53 × 10−1 | 7.93 × 104 | 2.79 × 105 | 0.00 | 0.00 | 9.51 × 103 | 4.65 × 105 | 0.00 | 1.66 × 106 | 4.59 × 105 |
HBS21 | 9.75 × 10−4 | 8.89 × 10−3 | 0.00 | 6.59 × 10−3 | 1.15 × 10−3 | 2.87 × 10−3 | 1.72 × 10−3 | 5.16 × 10−3 | 2.06 × 10−1 | 1.03 × 105 | 4.50 × 104 | 0.00 | 6.07 × 105 | 2.62 × 104 | 6.98 × 105 | 8.14 × 106 | 5.81 × 106 | 3.39 × 105 |
Hand sanitizers | ||||||||||||||||||
HS22 | 4.59 × 10−3 | 0.00 | 0.00 | 0.00 | 0.00 | 1.86 × 10−2 | 2.44 × 10−2 | 1.16 × 10−1 | 2.73 × 10−1 | 2.18 × 104 | 0.00 | 0.00 | 0.00 | 0.00 | 1.07 × 105 | 5.75 × 105 | 2.58 × 105 | 2.56 × 105 |
HS23 | 4.59 × 10−3 | 4.30 × 10−3 | 0.00 | 0.00 | 0.00 | 1.58 × 10−2 | 1.43 × 10−2 | 1.83 × 10−1 | 4.16 × 10−1 | 2.18 × 104 | 9.30 × 104 | 0.00 | 0.00 | 0.00 | 1.27 × 105 | 9.77 × 105 | 1.64 × 105 | 1.68 × 105 |
Spot-removing creams | ||||||||||||||||||
SRC24 | 2.17 × 10−2 | 8.53 × 10−2 | 0.00 | 3.10 × 10−2 | 2.33 × 10−2 | 4.66 × 10−2 | 0.00 | 7.53 × 10−1 | 3.43 | 4.60 × 103 | 4.69 × 103 | 0.00 | 1.29 × 105 | 1.29 × 103 | 4.30 × 104 | 0.00 | 3.99 × 104 | 2.04 × 104 |
SRC25 | 1.86 × 10−2 | 0.00 | 6.21 × 10−3 | 1.55 × 10−2 | 8.53 × 10−2 | 3.10 × 10−2 | 1.55 × 10−1 | 6.21 | 1.51 | 5.37 × 103 | 0.00 | 4.83 × 104 | 2.58 × 105 | 3.52 × 102 | 6.44 × 104 | 9.02 × 104 | 4.83 × 103 | 4.64 × 104 |
Hand/body creams | ||||||||||||||||||
HBC26 | 5.26 × 10−2 | 3.10 × 10−1 | 1.24 × 10−2 | 1.55 × 10−2 | 1.86 × 10−1 | 4.64 × 10−2 | 7.59 × 10−1 | 1.90 | 4.46 | 1.90 × 103 | 1.29 × 103 | 2.42 × 104 | 2.58 × 105 | 1.61 × 102 | 4.31 × 104 | 1.85 × 104 | 1.58 × 104 | 1.57 × 104 |
HBC27 | 4.95 × 10−2 | 5.88 × 10−1 | 0.00 | 1.55 × 10−2 | 7.74 × 10−2 | 1.24 × 10−1 | 0.00 | 1.52 | 6.41 | 2.02 × 103 | 6.80 × 102 | 0.00 | 2.58 × 105 | 3.88 × 102 | 1.61 × 104 | 0.00 | 1.98 × 104 | 1.09 × 104 |
Tolerable daily intake/RDA | (0.35a) (1b) |
3.6 | 200*b (3.3) | 5000*c (83) | 100*d (1.7) | 720**d (12) | 10−18**e | 12000*e | 12500*e |