Table 5.
Systemic Exposure Dosage (SED) |
Margin of Safety (MoS) |
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Cd | Pb | Cr | Cu | Co | Ni | Mn | Zn | Fe | Cd | Pb | Cr | Cu | Co | Ni | Mn | Zn | Fe | |
Household detergents | ||||||||||||||||||
HD1 | 6.88 × 10−4 | 5.16 × 10−3 | 0.00 | 4.01 × 10−3 | 7.45 × 10−3 | 8.03 × 10−3 | 0.00 | 2.81 × 10−2 | 1.30 × 10−1 | 1.45 × 105 | 7.75 × 104 | 0.00 | 9.97 × 105 | 4.03 × 103 | 2.49 × 105 | 0.00 | 1.07 × 106 | 5.40 × 105 |
HD2 | 9.17 × 10−4 | 5.73 × 10−3 | 0.00 | 3.44 × 10-03 | 8.03 × 10−3 | 7.45 × 10−3 | 3.44 × 10−3 | 3.67 × 10−2 | 1.42 × 10−1 | 1.09 × 105 | 6.98 × 104 | 0.00 | 1.16 × 106 | 3.74 × 103 | 2.68 × 105 | 4.07 × 106 | 8.18 × 105 | 4.92 × 105 |
HD3 | 6.88 × 10−4 | 4.01 × 10−3 | 0.00 | 4.59 × 10−3 | 8.60 × 10−3 | 8.60 × 10−3 | 0.00 | 5.91 × 10−2 | 1.57 × 10−1 | 1.45 × 105 | 9.97 × 104 | 0.00 | 8.72 × 105 | 3.49 × 103 | 2.33 × 105 | 0.00 | 5.08 × 105 | 4.46 × 105 |
HD4 | 6.19 × 10−3 | 5.39 × 10−2 | 0.00 | 6.31 × 10−3 | 9.17 × 10−3 | 1.20 × 10−2 | 8.03 × 10−3 | 9.23 × 10−2 | 3.69 × 10−1 | 1.61 × 104 | 7.42 × 103 | 0.00 | 6.34 × 105 | 3.27 × 103 | 1.66 × 105 | 1.74 × 106 | 3.25 × 105 | 1.90 × 105 |
HD5 | 1.15 × 10−3 | 6.31 × 10−3 | 0.00 | 4.59 × 10−3 | 1.09 × 10-2 | 1.43 × 10−2 | 3.44 × 10−3 | 6.13 × 10−2 | 1.96 × 10−1 | 8.72 × 104 | 6.34 × 104 | 0.00 | 8.72 × 105 | 2.75 × 103 | 1.40 × 105 | 4.07 × 106 | 4.89 × 105 | 3.57 × 105 |
HD6 | 1.72 × 10−3 | 1.15 × 10−2 | 0.00 | 2.29 × 10−3 | 7.45 × 10−3 | 1.03 × 10−2 | 0.00 | 3.61 × 10−2 | 1.48 × 10−1 | 5.81 × 104 | 3.49 × 104 | 0.00 | 1.74 × 106 | 4.03 × 103 | 1.94 × 105 | 0.00 | 8.31 × 105 | 4.73 × 105 |
HD7 | 8.03 × 10−4 | 1.03 × 10−2 | 6.88 × 10−3 | 4.59 × 10−3 | 6.31 × 10−3 | 9.17 × 10−3 | 3.44 × 10−3 | 2.64 × 10−2 | 3.21 × 10−1 | 1.25 × 105 | 3.88 × 104 | 4.36 × 104 | 8.72 × 105 | 4.76 × 103 | 2.18 × 105 | 4.07 × 106 | 1.14 × 106 | 2.18 × 105 |
HD8 | 1.03 × 10−3 | 5.73 × 10−3 | 3.69 × 10−2 | 8.60 × 10−3 | 8.60 × 10−3 | 1.38 × 10−2 | 1.66 × 10−2 | 4.19 × 10−2 | 2.30 × 10−1 | 9.69 × 104 | 6.98 × 104 | 8.13 × 103 | 4.65 × 105 | 3.49 × 103 | 1.45 × 105 | 8.42 × 105 | 7.17 × 105 | 3.04 × 105 |
HD9 | 1.15 × 10-03 | 1.89 × 10−2 | 3.60 × 10−2 | 2.87 × 10−3 | 8.03 × 10−3 | 1.38 × 10−2 | 1.15 × 10−2 | 5.91 × 10−2 | 1.94 × 10−1 | 8.72 × 104 | 2.11 × 104 | 8.33 × 103 | 1.40 × 106 | 3.74 × 103 | 1.45 × 105 | 1.22 × 106 | 5.08 × 105 | 3.61 × 105 |
HD10 | 2.06 × 10−3 | 2.75 × 10−2 | 1.15 × 10−3 | 5.73 × 10−3 | 1.09 × 10−2 | 1.72 × 10−2 | 1.38 × 10−2 | 5.16 × 10−2 | 2.17 × 10−1 | 4.84 × 104 | 1.45 × 104 | 2.62 × 105 | 6.98 × 105 | 2.75 × 103 | 1.16 × 105 | 1.02 × 106 | 5.81 × 105 | 3.23 × 105 |
Household liquid soaps | ||||||||||||||||||
HLS11 | 2.87 × 10−3 | 1.78 × 10−2 | 3.33 × 10−3 | 0.00 | 1.15 × 10−3 | 6.88 × 10−3 | 0.00 | 3.96 × 10−2 | 7.16 × 10−2 | 3.49 × 104 | 2.25 × 104 | 9.02 × 104 | 0.00 | 2.62 × 104 | 2.91 × 105 | 0.00 | 7.58 × 105 | 9.78 × 105 |
HLS12 | 1.95 × 10−3 | 4.59 × 10−3 | 4.01 × 10−3 | 0.00 | 1.15 × 10−3 | 7.45 × 10−3 | 5.73 × 10−4 | 6.42 × 10−2 | 1.07 × 10−1 | 5.13 × 104 | 8.72 × 104 | 7.48 × 104 | 0.00 | 2.62 × 104 | 2.68 × 105 | 2.44 × 107 | 4.67 × 105 | 6.57 × 105 |
HLS13 | 4.59 × 10−4 | 5.16 × 10−3 | 1.49 × 10−3 | 5.73 × 10−4 | 5.73 × 10−3 | 5.73 × 10−3 | 3.61 × 10−2 | 9.14 × 10−2 | 2.18 × 105 | 7.75 × 104 | 2.01 × 105 | 6.98 × 106 | 5.23 × 103 | 0.00 | 2.44 × 106 | 8.31 × 105 | 7.66 × 105 | |
Household bar soaps | ||||||||||||||||||
HBS14 | 1.49 × 10−3 | 2.87 × 10−3 | 0.00 | 2.29 × 10−3 | 3.44 × 10−3 | 6.88 × 10−3 | 1.72 × 10−3 | 5.56 × 10−2 | 2.37 × 10−1 | 6.71 × 104 | 1.40 × 105 | 0.00 | 1.74 × 106 | 8.72 × 103 | 2.91 × 105 | 8.14 × 106 | 5.39 × 105 | 2.95 × 105 |
HBS15 | 1.15 × 10−3 | 8.03 × 10−3 | 5.01 × 10−2 | 4.01 × 10−3 | 8.03 × 10−3 | 1.32 × 10−2 | 6.88 × 10−3 | 4.64 × 10−2 | 4.98 × 10−1 | 8.72 × 104 | 4.98 × 104 | 5.99 × 103 | 9.97 × 105 | 3.74 × 103 | 1.52 × 105 | 2.03 × 106 | 6.46 × 105 | 1.41 × 105 |
HBS16 | 6.88 × 10−4 | 6.31 × 10−3 | 0.00 | 1.72 × 10−3 | 3.44 × 10−3 | 6.88 × 10−3 | 6.31 × 10−3 | 4.41 × 10−2 | 2.00 × 10−1 | 1.45 × 105 | 6.34 × 104 | 0.00 | 2.33 × 106 | 8.72 × 103 | 2.91 × 105 | 2.22 × 10 6 | 6.80 × 105 | 3.51 × 105 |
HBS17 | 1.83 × 10−3 | 2.29 × 10−3 | 3.81 × 10−2 | 2.87 × 10−3 | 2.29 × 10−3 | 8.03 × 10−3 | 0.00 | 3.55 × 10−2 | 1.86 × 10−1 | 5.45 × 104 | 1.74 × 105 | 7.88 × 103 | 1.40 × 106 | 1.31 × 104 | 2.49 × 105 | 0.00 | 8.44 × 105 | 3.77 × 105 |
HBS18 | 5.73 × 10−4 | 5.73 × 10−4 | 0.00 | 2.29 × 10−3 | 2.87 × 10−3 | 8.03 × 10−3 | 1.38 × 10−2 | 4.87 × 10−2 | 2.36 × 10−1 | 1.74 × 105 | 6.98 × 105 | 0.00 | 1.74 × 10 6 | 1.05 × 104 | 2.49 × 105 | 1.02 × 106 | 6.16 × 105 | 2.96 × 105 |
HBS19 | 1.03 × 10−3 | 2.87 × 10−3 | 0.00 | 4.01 × 10−3 | 3.44 × 10−3 | 6.88 × 10−3 | 1.72 × 10−2 | 7.74 × 10−1 | 2.49 × 10−1 | 9.69 × 104 | 1.40 × 105 | 0.00 | 9.97 × 105 | 8.72 × 103 | 2.91 × 105 | 8.14 × 105 | 3.88 × 104 | 2.81 × 105 |
HBS20 | 2.52 × 10−3 | 2.87 × 10−3 | 0.00 | 0.00 | 6.31 × 10−3 | 8.60 × 10−3 | 0.00 | 3.61 × 10−2 | 3.05 × 10−1 | 3.96 × 104 | 1.40 × 105 | 0.00 | 0.00 | 4.76 × 103 | 2.33 × 105 | 0.00 | 8.31 × 105 | 2.29 × 105 |
HBS21 | 1.95 × 10−3 | 1.78 × 10−2 | 0.00 | 1.32 × 10−2 | 2.29 × 10−3 | 5.73 × 10−3 | 3.44 × 10−3 | 1.03 × 10−2 | 4.13 × 10−1 | 5.13 × 104 | 2.25 × 104 | 0.00 | 3.03 × 105 | 1.31 × 104 | 3.49 × 105 | 4.07 × 106 | 2.91 × 106 | 1.70 × 105 |
Hand sanitizers | ||||||||||||||||||
HS22 | 9.17 × 10−3 | 0.00 | 0.00 | 0.00 | 0.00 | 3.73 × 10−2 | 4.87 × 10−2 | 2.32 × 10−1 | 5.47 × 10−1 | 1.09 × 104 | 0.00 | 0.00 | 0.00 | 0.00 | 5.37 × 104 | 2.87 × 105 | 1.29 × 105 | 1.28 × 105 |
HS23 | 9.17 × 10−3 | 8.60 × 10−3 | 0.00 | 0.00 | 0.00 | 3.15 × 10−2 | 2.87 × 10−2 | 3.67 × 10−1 | 8.31 × 10−1 | 1.09 × 104 | 4.65 × 104 | 0.00 | 0.00 | 0.00 | 6.34 × 104 | 4.88 × 105 | 8.18 × 104 | 8.42 × 104 |
Spot-removing creams | ||||||||||||||||||
SRC24 | 4.34 × 10−2 | 1.71 × 10−1 | 0.00 | 6.21 × 10−2 | 4.66 × 10−2 | 9.31 × 10−2 | 0.00 | 1.51 | 6.86 | 2.30 × 103 | 2.34 × 103 | 0.00 | 6.44 × 104 | 6.44 × 102 | 2.15 × 104 | 0.00 | 1.99 × 104 | 1.02 × 104 |
SRC25 | 3.72 × 10−2 | 0.00 | 1.24 × 10−2 | 3.10 × 10−2 | 1.71 × 10−1 | 6.21 × 10−2 | 3.10 × 10−1 | 1.24 × 101 | 3.02 | 2.69 × 103 | 0.00 | 2.42 × 104 | 1.29 × 105 | 1.76 × 102 | 3.22 × 104 | 4.51 × 104 | 2.42 × 103 | 2.32 × 104 |
Hand/body creams | ||||||||||||||||||
HBC26 | 1.05 × 10−1 | 6.19 × 10−1 | 2.48 × 10−2 | 3.10 × 10−2 | 3.72 × 10−1 | 9.29 × 10−2 | 1.52 | 3.81 | 8.92 | 9.50 × 102 | 6.46 × 102 | 1.21 × 104 | 1.29 × 105 | 8.07 × 101 | 2.15 × 104 | 9.23 × 103 | 7.88 × 103 | 7.85 × 103 |
HBC27 | 9.91 × 10−2 | 1.18 | 0.00 | 3.10 × 10−2 | 1.55 × 10−1 | 2.48 × 10−1 | 0.00 | 3.03 | 1.28 × 101 | 1.01 × 103 | 3.40 × 102 | 0.00 | 1.29 × 105 | 1.94 × 102 | 8.07 × 103 | 0.00 | 9.89 × 103 | 5.46 × 103 |
Tolerable daily intake/RDA | (0.35a) (1b) | 3.6 | 200*b (3.3) | 5000*c (83) | 100*d (1.7) | 720**d (12) | 10−18**f | 12000*f | 12500*f |