Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 29;18:24–33. doi: 10.1016/j.omtn.2019.07.012

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

UCA1 Affects Apoptosis and Migration of Ovarian Cancer In Vitro

(A) Flow cytometry analysis showed that overexpression of Cdr1as promoted the cisplatin-induced cell apoptosis of resistant ovarian cancer in the presence of cisplatin (20 μM). (B) Flow cytometry analysis showed that inhibition of Cdr1as significantly decreased the cisplatin-induced cell apoptosis of resistant ovarian cancer in the presence of cisplatin (20 μM). (C) Transwell assay showed that deregulation of Cdr1as significantly promoted the migratory capacities of A2780 and SKOV-3 cells in the presence of cisplatin (20 μM). (D) Transwell assay showed that overexpression of Cdr1as dramatically decreased the migration capacity of A2780-DDP and SKOV-3-DDP cell lines in the presence of cisplatin (20 μM). All tests were performed at least three times. Data were expressed as mean ± SD. **p < 0.01.