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. 2019 Jul 29;18:24–33. doi: 10.1016/j.omtn.2019.07.012

Figure 4.

Figure 4

Cdr1as Functioned as a Molecular Sponge of miR-1270 in Ovarian Cancer Cells

(A) StarBase v2.0 results showing the sequence of Cdr1as with highly conserved putative miR-1270 binding sites. (B) miR-1270 mimic considerably reduced the luciferase activity of the WT-Cdr1as luciferase reporter vector compared with negative control, whereas miR-1270 mimic did not pose any impact on the luciferase activity of MUT-Cdr1as-transfected cells. (C) Cdr1as and miR-1270 simultaneously existed in the production precipitated by anti-AGO2. All tests were performed at least three times. Data were expressed as mean ± SD. **p < 0.01.