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. 2019 Jul 29;18:24–33. doi: 10.1016/j.omtn.2019.07.012

Figure 5.

Figure 5

miR-1270 Plays an Oncogenic Role in Ovarian Cancer Cells and Reduces Their Cisplatin Chemosensitivity

(A) Relative expression of miR-1270 in the cisplatin-sensitive group and cisplatin-resistant group in ovarian cancer patients. (B) Relative expression of miR-1270 in a panel of ovarian cancer cell lines. (C) CCK-8 assay showed that the miR-1270 inhibitor markedly inhibited the cell growth of A2780-DDP cells when compared with cells transfected with miR-NC. (D) CCK-8 assay showed that miR-1270 inhibitor markedly inhibits the cell growth of SKOV-3-DDP cells when compared with cells transfected with miR-NC. (E) CCK-8 assay showed that miR-1270 overexpression markedly promoted the proliferation of A2780 cells when compared with cells transfected with miR-NC. (F) CCK-8 assay showed that miR-1270 overexpression markedly promoted the proliferation of SKOV-3 cells when compared with cells transfected with miR-NC. All tests were performed at least three times. Data were expressed as mean ± SD. **p < 0.01.